Rab5a Antibody (3A4) Summary
Immunogen |
Recombinant human Rab5a (1-215aa) purified from E. coli
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Marker |
Early Endosome Marker
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Specificity |
Anti-human Rab5a mAb, clone 3A4, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Rab5a protein.
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Isotype |
IgG2b Kappa
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Clonality |
Monoclonal
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Host |
Mouse
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Gene |
RAB5A
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Purity |
Protein G purified
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Applications/Dilutions
Dilutions |
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Reactivity Notes
May also react with Mouse.
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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Buffer |
PBS (pH 7.4) and 10% Glycerol
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Preservative |
0.02% Sodium Azide
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Concentration |
1.0 mg/ml
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Purity |
Protein G purified
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Alternate Names for Rab5a Antibody (3A4)
- RAB5A, member RAS oncogene family
- RAB5RAS-associated protein RAB5A
- ras-related protein Rab-5A
Background
Rab5a is a member of the RAS oncogene family. Rab5a is a small GTPase localized to the plasma membrane and early endosomes. It is a crucial regulatory component of the endocytic pathway. Activation of Rab5a is mediated by GDP-GTP exchange factors (GEFs) that generate the Rab5-GTP complex.