Recombinant Human LYVE-1 Protein Summary
| Description |
A recombinant protein corresponding to amino acids 25 – 235 of LYVE1.
Amino Acid Sequence: ADPLRAEELSIQVSCRIMGITLVSKKANQQLNFTEAKEACRLLGLSLAGKDQVETALKASFETCSYGWVGDGFVVISRISPNPKCGKNGVGVLIRKVPVSRQFAAYCYNSSDTWTNSCIPEIITTKDPIFNTQTATQTTEFIVSDSTYSVASPYSTIPAPTTTPPAPASTSIPRRKKLICVTEVFMETSTMSTETEPFVENKAAFKNEAAGFGGSGRLVPRGSHHHHHH |
| Preparation Method |
Hi-5
|
| Protein/Peptide Type |
Recombinant Protein
|
| Gene |
LYVE1
|
| Purity |
>90%, by SDS-PAGE
|
Applications/Dilutions
| Theoretical MW |
24.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Store at -80C. Avoid freeze-thaw cycles.
|
| Buffer |
20mM Tris pH7.5, 10% glycerol
|
| Preservative |
No Preservative
|
| Concentration |
1.0 mg/ml
|
| Purity |
>90%, by SDS-PAGE
|
Notes
The purity of this protein is > 90% by SDS-PAGE. Molecular weight is 24.8 kDa (229 aa), confirmed by MALDI-TOF.
Alternate Names for Recombinant Human LYVE-1 Protein
- cell surface retention sequence binding protein-1
- Cell surface retention sequence-binding protein 1
- CRSBP1
- CRSBP-1
- extracellular link domain containing 1
- extracellular link domain-containing 1
- Extracellular link domain-containing protein 1
- HAR
- Hyaluronic acid receptor
- lymphatic vessel endothelial hyaluronan receptor 1
- lymphatic vessel endothelial hyaluronic acid receptor 1
- LYVE1
- LYVE-1
- LYVE-1XLKD1
- XLKD1
Background
Lymphatic vascular endothelial hyaluronan receptor-1 (LYVE-1), a selective marker of the lymphatic endothelium, is a surface endocytic receptor for hyaluronan (HA), which is an extracellular glycosaminoglycan involved in cell adhesion and migration. LYVE1 is also known as XLKD1 and may function in lympathic hyaluronan transport and have a role in tumor metastasis. Recombinant human LYVE1 was expressed in High Five insect cells and purified by conventional chromatography techniques. As a result of glycosylation, the size of molecular weight will be shift-up as an approximately 50 kDa on SDS-PAGE analysis.
