Recombinant Human S100A10 Protein Summary
| Description |
A recombinant protein with a His-tag corresponding to amino acids 1 to 97 of Human S100A10
Source: E. coli Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MPSQMEHAME TMMFTFHKFA GDKGYLTKED LRVLMEKEFP GFLENQKDPL AVDKIMKDLD QCRDGKVGFQ SFFSLIAGLT IACNDYFVVH MKQKGKK |
| Preparation Method |
E.coli
|
| Protein/Peptide Type |
Recombinant Protein
|
| Gene |
S100A10
|
| Purity |
>90%, by SDS-PAGE
|
Applications/Dilutions
| Application Notes |
The purity of this protein is > 90% by SDS-PAGE. Molecular weight is 13.3 kDa (117aa) confirmed by MALDI-TOF
|
| Theoretical MW |
13.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Store at -80C. Avoid freeze-thaw cycles.
|
| Buffer |
20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol, 0.1M NaCl, 0.1mM PMSF
|
| Concentration |
1 mg/ml
|
| Purity |
>90%, by SDS-PAGE
|
Alternate Names for Recombinant Human S100A10 Protein
- annexin II ligand, calpactin I, light polypeptide
- ANX2L
- ANX2LG
- CAL1LGP11,42C
- Calpactin I light chain
- Calpactin-1 light chain
- Cellular ligand of annexin II
- CLP11Ca[1]
- MGC111133
- p10 protein
- p10
- P11
- protein S100-A10
- S100 calcium binding protein A10 (annexin II ligand, calpactin I, lightpolypeptide (p11))
- S100 calcium binding protein A10
- S100 calcium-binding protein A10 (annexin II ligand, calpactin I, lightpolypeptide (p11))
- S100 calcium-binding protein A10
- S100A10
Background
S100 calcium binding protein A10, also known S100A10, is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A10 is primarily found in mast cells as heterotetrameric complexes that are present intracellularly at the plasma membrane or on the extracellular cell surface. Extracellular S100A10 is a key plasminogen receptor that plays an important role in cellular plasmin production and cellular invasiveness. Recombinant human S100A10 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
