SOD2/Mn-SOD Antibody Summary
| Immunogen |
SOD2 (AAH12423.1, 1 a.a. – 222 a.a.) full-length human protein. MLSRAVCGTSRQLAPVLGYLGSRQKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK
|
| Specificity |
Reacts with superoxide dismutase 2, mitochondrial.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
SOD2
|
| Purity |
Protein A purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
This antibody is reactive against tissue and transfected lysate in WB and as a detection antibody in ELISA.
|
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
Protein A purified
|
Notes
Quality control test: Antibody reactive against mammalian transfected lysate.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for SOD2/Mn-SOD Antibody
- EC 1.15.1.1
- indophenoloxidase B
- IPOB
- IPO-B
- manganese-containing superoxide dismutase
- mangano-superoxide dismutase
- Mn SOD
- Mn superoxide dismutase
- MnSOD
- MVCD6
- SOD, Mitochodrial
- SOD2
- superoxide dismutase [Mn], mitochondrial
- superoxide dismutase 2, mitochondrial
Background
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
