SP-B/Surfactant Protein B Antibody Summary
| Immunogen |
SFTPB (NP_000533.2, 1 a.a. – 381 a.a.) full-length human protein. MAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALAVAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSECHLCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMSSPLQCIHSPDL
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| Specificity |
Reacts with surfactant protein B.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
SFTPB
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| Purity |
Protein A purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is reactive against transfected lysate in WB and as a detection antibody in ELISA.
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Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
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| Buffer |
PBS (pH 7.4)
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| Preservative |
No Preservative
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| Purity |
Protein A purified
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Notes
Quality control test: Antibody reactive against mammalian transfected lysate.
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for SP-B/Surfactant Protein B Antibody
- 18 kDa pulmonary-surfactant protein
- 6 kDa protein
- PSP-B
- pulmonary surfactant-associated protein B
- Pulmonary surfactant-associated proteolipid SPL(Phe)
- SFTB3
- SFTP3
- SMDP1
- SP-B surfactant, pulmonary-associated protein B
- surfactant protein B
Background
The SFTPB gene encodes the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Surfactant is composed of phospholipids and other surfactant-associated proteins (Clark et al., 1995 [PubMed 7644495]). See also SFTPA1 (MIM 178630), SFTPC (MIM 178620), and SFTPD (MIM 178635).[supplied by OMIM]
