Siglec-2/CD22 Antibody (MEM-01) [DyLight 755]

Siglec-2/CD22 Antibody (MEM-01) [DyLight 755] Summary

Immunogen	Raji Burkitts lymphoma cell line
Epitope	The antibody MEM-01 cross-blocks the antibody OTH228 that recognizes uniquely epitope “E”; it does not cross-block antibodies RFB-4, CLB22/1 and CLB-BLy1.
Localization	Type I membrane protein
Specificity	The antibody MEM-01 reacts with CD22 (BL-CAM), a 130 kDa type I transmembrane glycoprotein (immunoglobulin superfamily) expressed in the cytoplasm of pro-B and pre-B lymphocytes, and on the surface of mature and activated B lymphocytes; it is lost on plasma cells, peripheral blood T lymphocytes, granulocytes and monocytes.
Isotype	IgG1
Clonality	Monoclonal
Host	Mouse
Gene	CD22
Purity	Protein A purified
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Dilutions	Western Blot Flow Cytometry
Application Notes	The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW	95 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.