Product: Phorbol 12-myristate 13-acetate
Src [p Tyr418] Antibody Summary
| Immunogen |
A phospho specific peptide corresponding to residues surrounding Y418 of human SRC
|
| Modification |
p Tyr418
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
SRC
|
| Purity |
Affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Theoretical MW |
60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
May react to Mouse and Rat
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS and 50% glycerol, pH7.3.
|
| Preservative |
0.02% Sodium Azide
|
| Purity |
Affinity purified
|
Alternate Names for Src [p Tyr418] Antibody
- ASV
- c-Src
- EC 2.7.10
- EC 2.7.10.2
- pp60c-src
- Rous sarcoma
- RSVgp4
- Src
- tyrosine kinase pp60c-src
- tyrosine-protein kinase SRC-1
- v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
- v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
Background
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
