TAB2 Antibody (3B5) Summary
| Immunogen |
Purified recombinant fragment of human TAB2 expressed in E. Coli.
|
| Isotype |
IgG1
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
TAB2
|
| Purity |
Unpurified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
This antibody is useful in Western Blot, ELISA, Flow Cytometry. Although not tested this anitbody may be useful in Immunofluorescence/Immunocytochemistry.
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
Ascites
|
| Preservative |
0.03% Sodium Azide
|
| Purity |
Unpurified
|
Alternate Names for TAB2 Antibody (3B5)
- FLJ21885
- KIAA0733CHTD2
- MAP3K7IP2mitogen-activated protein kinase kinase kinase 7 interacting protein 2
- Mitogen-activated protein kinase kinase kinase 7-interacting protein 2
- TAB-2
- TAK1-binding protein 2
- TGF-beta activated kinase 1/MAP3K7 binding protein 2
- TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
- TGF-beta-activated kinase 1-binding protein 2
Background
The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. [provided by RefSeq]
