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Product: TAK-779

TARBP1 Antibody Summary

Immunogen
This antibody is specific for the N Terminus Region of the target protein.
Specificity
This product is specific for Human TARBP1.
Clonality
Polyclonal
Host
Rabbit
Gene
TARBP1
Purity
Immunogen affinity purified
Innovators Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
Publications
Read Publications using 30720002.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

Manufactured by SDIXs proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for TARBP1 Antibody

  • EC 2.1.1.-
  • FLJ30482
  • TAR (HIV-1) RNA binding protein 1
  • TAR RNA loop binding protein
  • TAR RNA-binding protein 1
  • TAR RNA-binding protein of 185 kDa
  • tardbp1
  • TRM3probable methyltransferase TARBP1
  • TRP-185TAR (HIV) RNA binding protein 1
  • TRP185TAR (HIV) RNA-binding protein 1

Background

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. This element forms a stable stem-loop structure and can be bound by either the protein encoded by this gene or by RNA polymerase II. This protein may act to disengage RNA polymerase II from TAR during transcriptional elongation. Alternatively spliced transcripts of this gene may exist, but their full-length natures have not been determined.

PMID: 23365423

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Author: premierroofingandsidinginc

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Product: Evans Blue

TARBP1 Antibody Summary

Immunogen
Antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRBP1. The immunogen is located within amino acids 1310 – 1360 of TRBP1.
Clonality
Polyclonal
Host
Rabbit
Gene
TARBP1
Purity
Immunogen affinity purified
Innovators Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Learn about the Innovators Reward

Applications/Dilutions

Dilutions
  • Western Blot 1-2 ug/ml
  • ELISA 1:100-1:2000
Application Notes
TRBP1 antibody can be used for detection of TRBP1 by Western blot at 1 – 2 mg/ml.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Theoretical MW
182 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
TARBP1 Peptide (NBP1-76400PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TARBP1 Antibody

  • EC 2.1.1.-
  • FLJ30482
  • TAR (HIV-1) RNA binding protein 1
  • TAR RNA loop binding protein
  • TAR RNA-binding protein 1
  • TAR RNA-binding protein of 185 kDa
  • tardbp1
  • TRM3probable methyltransferase TARBP1
  • TRP-185TAR (HIV) RNA binding protein 1
  • TRP185TAR (HIV) RNA-binding protein 1

Background

The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1alpha (EF-1alpha), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.

PMID: 9327720

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Author: premierroofingandsidinginc