TMPRSS3 Antibody Summary
| Immunogen |
Peptide with sequence C-EKIVYHSKYKPKR corresponding to internal region according to NP_076927.1, NP_115777.1, NP_115780.1, NP_115781.1.
|
| Epitope |
EKIVYHSKYKPKR
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| Specificity |
This antibody is expected to recognise all four reported isoforms (NP_076927.1; NP_115777.1; NP_115780.1; NP_115781.1)
|
| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
TMPRSS3
|
| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Approx. 48 kDa band observed in A431 lysates (calculated MW of 49.4 kDa band according to NP_076927.1).
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| Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Mouse.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
|
| Preservative |
0.02% Sodium Azide
|
| Concentration |
0.5 mg/ml
|
| Purity |
Immunogen affinity purified
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Alternate Names for TMPRSS3 Antibody
- DFNB10
- DFNB8
- EC 3.4.21
- EC 3.4.21.-
- gene similar to transmembrane serine protease10ECHOS1Serine protease TADG-12
- serine protease TADG12
- TADG12
- transmembrane protease serine 3
- transmembrane protease, serine 3
- Tumor-associated differentially-expressed gene 12 protein
Background
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor associated gene that is overexpressed in ovarian tumors. Four alternatively spliced variants have been described, two of which encode identical products.
