Product: Pantoprazole (sodium hydrate)
UNC5CL Antibody Summary
| Immunogen |
Recombinant human ZUD domain (aa 402-518).
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
UNC5CL
|
| Purity |
Protein A purified
|
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|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Human and Mouse
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.02% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Protein A purified
|
Alternate Names for UNC5CL Antibody
- MGC34763
- Protein unc-5 homolog C-like
- unc-5 homolog C (C. elegans)-like
- ZU5 and death domain containing
- ZU5 and death domain-containing protein
- ZUDUNC5C-like protein
Background
ZUD is cytoplasmic protein with a ZU5 and death domain. It interacts with the NF-?B subunit p105 and transactivator p65 and inhibits NF-?B -dependent transcription when its overexpressed. ZUD seems to be a inhibitor of NF-?B signalling, and enhance cell death to apoptotic stimuli like TNF and TRAIL.
