UT2/SLC14A2 Antibody Summary
| Immunogen |
Produced against a synthetic peptide mapped to the C-terminal tail (amino acids 911-929) of rat UT-A1 (antibody designation L194)
|
| Localization |
Cell Membrane, Apical Cell Membrane
|
| Specificity |
Detects approx 97 and 127kDa.
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
SLC14A2
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
1 ug/ml of UT-A1 Antibody was sufficient for detection of UT-A1 in 20 ug of rat kidney tissue lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary Antibody.
|
Reactivity Notes
Based on homology, Its predicted to detect Mouse.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
PBS and 50% Glycerol
|
| Preservative |
0.9% Sodium Azide
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for UT2/SLC14A2 Antibody
- FLJ16167
- HUT2UT-A2
- hUT-A6
- MGC119566
- SLC14A2
- solute carrier family 14 (urea transporter), member 2
- Solute carrier family 14 member 2
- urea transporter 2
- Urea transporter, kidney
- urea transporter-2
- UT2
- UT2MGC119567
- UTA
- UT-A2
- UTR
Background
UT-A1, a kidney-specific urea transporter is expressed in the renal collecting duct where it mediates transepithelial urea transport and is a target for regulation by vasopressin. Urea movement out of the collecting duct in the inner medulla of the kidney allows accumulation of urea in the medullary interstitium, thereby allowing maximum water reabsorption from the collecting ducts. (The antibody also recognizes a second protein from the UT-A gene driven by transcription from an alternative promotor and expressed in the thin descending limb of Henle, viz. UT-A2.) (1, 2)
