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Product: AMG-3969

VAMP-1 Antibody Summary

Immunogen
A synthetic peptide as a part of rat, mouse Vesicle-associated membrane protein 1 conjugated to an immunogenic carrier protein was used as the immunogen.
Specificity
VAMP1.
Clonality
Polyclonal
Host
Sheep
Gene
VAMP1
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot 10-50 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Rat and Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
IgG purified
Reconstitution Instructions
Reconstitute with 0.5 ml sterilized water. Add glycerol (1:1) for additional stability.

Alternate Names for VAMP-1 Antibody

  • DKFZp686H12131
  • SYB1
  • SYB1vesicle-associated membrane protein 1
  • synaptobrevin 1
  • Synaptobrevin-1
  • VAMP1
  • VAMP-1
  • VAMP-1synaptobrevin-1
  • vesicle-associated membrane protein 1 (synaptobrevin 1)

Background

FUNCTION: Involved in the targeting and/or fusion of transport vesicles to their target membrane.; SUBUNIT: Interacts with VAPA and VAPB. SUBCELLULAR LOCATION: Isoform 1: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome. SUBCELLULAR LOCATION: Isoform 2: Cytoplasmic vesicle membrane; Single-pass type IV membrane protein. Note: Isoforms 2 and 3 are found in perinuclear as well as peripheral punctate structures in osteoblasts. SUBCELLULAR LOCATION: Isoform 3: Mitochondrion outer membrane; Single-pass type IV membrane protein. Note=Isoforms 2 and 3 are found in perinuclear as well as peripheral punctate structures in osteoblasts. TISSUE SPECIFICITY: Expressed in brain and spleen (at protein level). Isoform 1 expressed at very high level in brain. Even higher level found in spinal cord. Isoform 3 expressed in kidney, spleen and liver. Isoforms 2 and 3 expressed in osteoblasts of trabecular bone. Also expressed in heart.

PMID: 1335050

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Author: premierroofingandsidinginc