Virilizer Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residue 200 and 250 of human Virilizer (KIAA1429) using the numbering given in entry NP_056311.2 (GeneID 25962).
|
| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
KIAA1429
|
| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
|
| Application Notes |
It is not recommended for western analysis.
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
1.0 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Virilizer Antibody
- DKFZP434I116
- DKFZp781B2117
- fSAP121
- functional spliceosome-associated protein 121
- KIAA1429
- MGC138493
- MGC141940
- protein virilizer homolog
Background
The virilizer (vir) gene was discovered as a factor required for dosage compensation and sex determination in female flies. In drosophila it has been determined to function as a positive regulator of female-specific mRNA splicing. Database searches using the deduced amino acid sequence of the drosophila VIR retrieved a human protein BAA92667 (GenBank) which corresponds to the gene designated as KIAA1429. The human protein is 28% identical and about 40% similar to drosophila VIR and contains the putative transmembrane domain of drosophila VIR.
