ZMIZ2 Antibody Summary
| Immunogen |
Antibody was raised against a 17 amino acid synthetic peptide near the center of human ZIMP7. The immunogen is located within amino acids 270 – 320 of ZIMP7.
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| Specificity |
At least four isoforms are known to exist. ZIMP7 antibody is predicted to not cross-react with other PIAS protein family members.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
ZMIZ2
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Control Peptide |
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Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
PBS
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| Preservative |
0.02% Sodium Azide
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| Concentration |
1 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for ZMIZ2 Antibody
- hZIMP7
- KIAA1886ZIMP7DKFZp761I2123
- NET27
- PIAS-like protein Zimp7
- TRAFIP20
- zinc finger MIZ domain-containing protein 2
- zinc finger, MIZ-type containing 2
Background
ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.
