p130Cas/BCAR1 [p Tyr410] Antibody Summary
Immunogen |
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human p130Cas (phospho Tyr410). The exact sequence is proprietary
|
Modification |
p Tyr410
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Isotype |
IgG
|
Clonality |
Polyclonal
|
Host |
Rabbit
|
Gene |
BCAR1
|
Purity |
Antigen Affinity-purified
|
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Applications/Dilutions
Dilutions |
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Theoretical MW |
93 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
Buffer |
PBS, 1% BSA, 20% Glycerol (pH7).
|
Preservative |
0.025% Proclin 300
|
Concentration |
0.58 mg/ml
|
Purity |
Antigen Affinity-purified
|
Alternate Names for p130Cas/BCAR1 [p Tyr410] Antibody
- BCAR1
- breast cancer estrogen resistance 1
- Cas scaffolding protein family member 1
- CAS1
- CASFLJ45059
- CASS1
- CASS1CRKASbreast cancer estrogen resistance protein 1
- CRKAS
- Crk-associated substrate p130Cas
- CRK-associated substrate
- FLJ12176
- p130Cas
Background
BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion (Sawada et al., 2006 [PubMed 17129785]).[supplied by OMIM]