VPS45 Antibody Summary
| Immunogen |
Peptide with sequence C-ESSQVTSRSASRR corresponding to C-Terminus according to NP_009190.2.
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
VPS45
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Approx. 60 kDa band observed in human testis and peripheral blood mononucleocyte lysates (calculated MW of 65.1 kDa band according to NP_009190.2).
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| Positive Control |
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| Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Mouse, Canine, Bovine.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for VPS45 Antibody
- H1
- H1VPS45
- hlVps45
- h-vps45
- leucocyte vacuolar protein sorting 45
- vacuolar protein sorting 45 homolog (S. cerevisiae)
- vacuolar protein sorting 45A (yeast homolog)
- vacuolar protein sorting 45A (yeast)
- vacuolar protein sorting 45A
- vacuolar protein sorting-associated protein 45
- VPS45A
- VPS45AVPS54A
- VPS45B
- VSP45
- VSP45A
Background
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators.
