CHIP/STUB1 Antibody Summary
| Immunogen |
Peptide with sequence C-DAFISENGWVEDY corresponding to C-Terminus according to NP_005852.2.
|
| Clonality |
Polyclonal
|
| Host |
Goat
|
| Gene |
STUB1
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
||
| Application Notes |
WB: Approx. 35 kDa band observed in human muscle lysates (calculated MW of 34.9 kDa band according to NP_005852.2).
|
||
| Positive Control |
|
||
| Publications |
|
Reactivity Notes
Predicted cross-reactivity based on sequence identity: Mouse, Rat, Canine, Bovine.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
|
| Preservative |
0.02% Sodium Azide
|
| Concentration |
0.5 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for CHIP/STUB1 Antibody
- Antigen NY-CO-7
- Carboxy terminus of Hsp70-interacting protein
- CHIP
- CHIPSTIP1 homology and U box-containing protein 1
- CLL-associated antigen KW-8
- E3 ubiquitin-protein ligase CHIP
- EC 6.3.2.-
- heat shock protein A binding protein 2 (c-terminal)
- HSPABP2
- NY-CO-7
- SDCCAG7
- serologically defined colon cancer antigen 7
- STIP1 homology and U-box containing protein 1
- STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
- STUB1
- UBOX1
Background
STUB1 modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. It has E3 ubiquitin protein ligase activity and targets misfolded chaperone substrates towards proteasomal degradation. STUB1 mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation.
