Product: Pimelic Diphenylamide 108
HDAC1 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to the N-terminus of human Histone Deacetylase 1 using the numbering given in entry NP_004955.2 (GeneID 3065).
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| Predicted Species |
Monkey (100%), Guinea Pig (100%), Primate (100%), Canine (100%), Rabbit (100%). Backed by our 100% Guarantee.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
HDAC1
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| Purity |
Immunogen affinity purified
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| Innovators Reward |
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Applications/Dilutions
| Dilutions |
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| Application Notes |
This antibody is useful for Immunoprecipitation. Not recommended for Western Blot. Use rabbit anti-HDAC1 antibody NB 100-2241.
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| Positive Control |
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Reactivity Notes
Based on 100% sequence identity, this antibody is predicted to react with Panda, Orangutan, Rhesus Monkey, Gorilla, White-tufted-ear marmoset, European domestic ferret, Naked mole rat, Small-eared galago, Thirteen-lined ground squirrel and Northern white-cheeked gibbon.
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
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| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
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| Preservative |
0.09% Sodium Azide
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| Concentration |
1.0 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for HDAC1 Antibody
- EC 3.5.1.98
- GON-10
- HD1DKFZp686H12203
- histone deacetylase 1
- reduced potassium dependency, yeast homolog-like 1
- RPD3L1RPD3
Background
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
