Product: CEP-28124 (mesylate salt)
GRF2 Antibody Summary
| Immunogen |
The immunogen recognized by this antibody maps to a region between residue 375 and 425 of human CRK SH3-binding GNRP using the numbering given in entry NP_005303.2 (GeneID 2889).
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
RAPGEF1
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Positive Control |
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Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
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| Buffer |
TBS and 0.1% BSA
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| Preservative |
0.09% Sodium Azide
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| Concentration |
0.2 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for GRF2 Antibody
- C3GGRF2guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene)
- CRK SH3-binding GNRP
- DKFZp781P1719
- Guanine nucleotide-releasing factor 2
- Protein C3G
- Rap guanine nucleotide exchange factor (GEF) 1
- rap guanine nucleotide exchange factor 1
Background
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq]
