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Product: NSC305789

ARFGAP1 Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 356 and 406 of human ADP-ribosylation factor GTPase activating protein 1 using the numbering given in entry NP_060679.1 (GeneID 55738).
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Clonality
Polyclonal
Host
Rabbit
Gene
ARFGAP1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2-5 ug/mg lysate
Application Notes
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
45 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Based on 100% sequence identity, this antibody is predicted to react with Gorilla and Chimpanzee.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for ARFGAP1 Antibody

  • ADP-ribosylation factor 1 GTPase activating protein
  • ADP-ribosylation factor 1 GTPase-activating protein
  • ADP-ribosylation factor GTPase activating protein 1
  • ADP-ribosylation factor GTPase-activating protein 1
  • ARF GAP 1
  • ARF1 GAP
  • ARF1-directed GTPase-activating protein
  • ARF1GAP
  • bA261N11.3
  • FLJ10767
  • GAP protein
  • HRIHFB2281
  • MGC39924

Background

The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

PMID: 2825685

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Author: premierroofingandsidinginc