ABCE1 Antibody Summary
| Immunogen |
Peptide with sequence C-KLNSIKDVEQKK corresponding to C-Terminus according to NP_001035809.1.
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| Specificity |
Variants (NP_002931.2; NP_001035809.1) encode the same protein.
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
ABCE1
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Approx. 70 kDa band observed in lysates of A431 (calculated MW of 67.6 kDa band according to NP_002931.1).
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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| Theoretical MW |
67 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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| Positive Control |
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| Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Mouse, Rat, Canine, Bovine.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
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| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for ABCE1 Antibody
- 2-5-oligoadenylate-binding protein
- ATP-binding cassette, sub-family E (OABP), member 1
- huHP68
- OABP
- Ribonuclease 4 inhibitor
- ribonuclease L (2-5-oligoisoadenylate synthetase-dependent) inhibitor
- RLIABC38
- RNase L inhibitor
- RNASEL1
- RNASELIRNS4IATP-binding cassette sub-family E member 1
Background
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
