Alix Antibody Summary
| Immunogen |
The immunogen for this product maps to a region between residue 400 and 450 of human Apoptosis-Linked Gene 2-Interacting Protein X using the numbering given in entry NP_037506.2 (GeneID 10015).
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
PDCD6IP
|
| Purity |
Immunogen affinity purified
|
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Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
Tris-Citrate/Phosphate (pH 7.0 – 8.0)
|
| Preservative |
0.09% Sodium Azide
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Alix Antibody
- AIP1DRIP4
- ALG-2 interacting protein 1
- ALG-2 interacting protein X
- ALG-2-interacting protein 1
- alinx
- Alix
- apoptosis-linked gene 2-interacting protein X
- dopamine receptor interacting protein 4
- HP95
- KIAA1375
- MGC17003
- PDCD6-interacting protein
- programmed cell death 6 interacting protein
- programmed cell death 6-interacting protein
Background
This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization which may be partly responsible for the protection against cell death.
