Orc2 Antibody Summary
| Immunogen |
The immunogen for this product maps to a region between residue 150 and 200 of human Origin Recognition Complex, Subunit 2-like using the numbering given in entry NP_006181.1 (GeneID 4999).
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| Marker |
Chromatin Marker
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
ORC2
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| Purity |
Immunogen affinity purified
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| Innovators Reward |
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze.
|
| Buffer |
TBS and 0.1% BSA
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| Preservative |
0.09% Sodium Azide
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| Concentration |
0.2 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for Orc2 Antibody
- ORC2Lorigin recognition complex subunit 2
- origin recognition complex protein 2 homolog
- origin recognition complex, subunit 2 (yeast homolog)-like
- origin recognition complex, subunit 2 homolog (yeast)
- origin recognition complex, subunit 2 homolog
- origin recognition complex, subunit 2
- origin recognition complex, subunit 2-like (yeast)
- origin recognition complex, subunit 2-like
Background
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3L, -4L, and -5L. It also interacts with CDC45L and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication.
