Product: Promazine (hydrochloride)
CaM Kinase I Antibody Summary
| Immunogen |
Synthetic Peptide: A(1) V E G P R W K Q A E D I R D I Y D(18)
|
| Specificity |
Detects CaMKI from rat brain extract.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
CAMK1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
WB: Detects an approx. 43 kDa protein representing CaMKI from rat brain extract.
|
Reactivity Notes
Expected cross-reactivity with Human base on sequence homology.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS and 1 mg/ml BSA
|
| Preservative |
0.05% Sodium Azide
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for CaM Kinase I Antibody
- calcium/calmodulin-dependent protein kinase I
- calcium/calmodulin-dependent protein kinase type 1
- CaM kinase I alpha
- CaM Kinase I
- CAMKI
- caM-KI
- caMKI-alpha
- EC 2.7.11
- EC 2.7.11.17
- MGC120317
- MGC120318
Background
Calcium / calmodulin-dependent kinases (CaMKs) are a subfamily of the serine/threonine protein kinase family that includes CaMKI, CaMKII, and CaMKIV. There have been identified multiple substrates for CaMKI, including synapsin 1, synapsin 2, CREB, and CFTR, and its activation is dependent upon phosphorylation of Thr 177 by CaMK kinase (CaMKK). Studies suggest that CaMKI plays an important role in retinal function and its expression is regulated by light stimulation.
