PDE6G Antibody Summary
| Immunogen |
Synthetic Peptide: M(1) N L E P P K A E I R S A T R(15) C
|
| Specificity |
NB120-5664 detects phosphodiesterase 6 gamma (PDE6 gamma) from sheep retinal extract and bovine rod outer segment membranes as well as purified bovine PDE6 gamma.
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
PDE6G
|
| Purity |
Ammonium sulfate precipitation
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
WB: Detects an approx. 10 kDa protine representing PDE6 gamma from sheep retinal extract.
|
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS
|
| Preservative |
0.05% Sodium Azide
|
| Purity |
Ammonium sulfate precipitation
|
Alternate Names for PDE6G Antibody
- DKFZp686C0587
- GMP-PDE gamma
- MGC125749
- PDEG
- phosphodiesterase 6G, cGMP-specific, rod, gamma
- retinal rod rhodopsin-sensitive cGMP 3-5-cyclic phosphodiesterase subunit gamma
- rod cG-PDE G
- RP57
Background
This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants.
