cIAP-2/HIAP-1 Antibody Summary
| Immunogen |
Peptide with sequence C-SQPTFPSSVT corresponding to internal region according to NP_001156.1.
|
| Epitope |
C-SQPTFPSSVT
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| Specificity |
Reported variants represent identical protein: NP_892007.1, NP_001156.1
|
| Clonality |
Polyclonal
|
| Host |
Goat
|
| Gene |
BIRC3
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
|
| Application Notes |
WB: Approx. 70 kDa band observed in HeLa lysates (calculated MW of 68.4 kDa band according to NP_001156.1).
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| Publications |
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Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
|
| Preservative |
0.02% Sodium Azide
|
| Purity |
Immunogen affinity purified
|
Alternate Names for cIAP-2/HIAP-1 Antibody
- AIP1
- API2
- BIRC3 baculoviral IAP repeat containing 3
- BIRC3
- cIAP2
- c-IAP2
- cIAP-2
- HAIP1
- HIAP1
- HIAP-1
- MALT2
- MIHC
- RNF49
Background
cIAP2 is an apoptotic suppressor. Apoptosis is activated by an array of stimuli including members of the TNF family and can be prevented by the inhibitor of apoptosis (IAP) proteins. These proteins contain a baculovirus IAP repeat (BIR) domain which interact with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form a heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2). This complex may play a role in the inhibition of apoptosis.
