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Product: Molsidomine

Dystrophin Antibody (SPM499) Summary

Immunogen
Synthetic peptide corresponding to C-terminus of human dystrophin.
Specificity
This product is specific for Dystrophin
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
DMD
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50
Application Notes
IHC-P: Use at an assay dependent dilution. Staining of formalin fixed tissues requires boiling tissue sections in 10mMcitrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
10mM PBS (pH 7.4) and 1.0% BSA
Preservative
0.1% Sodium Azide
Purity
Protein A or G purified

Alternate Names for Dystrophin Antibody (SPM499)

  • BMDDXS272
  • CMD3B
  • DXS142
  • DXS164
  • DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272
  • DXS206
  • DXS230
  • DXS239
  • DXS268
  • DXS269
  • DXS270
  • dystrophin (muscular dystrophy, Duchenne and Becker types), includes DXS142
  • dystrophin

Background

Dystrophin is a member of the spectrin/alpha-actinin family of actin-binding, triple helix rod-containing proteins. It is absent or greatly reduced in individuals with the X-linked recessive Duchennes muscular dystrophy disorder, as well as in mice with the mdx (murine muscular dystrophy) mutation.

PMID: 10336422

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Author: premierroofingandsidinginc