Dystrophin Antibody (SPM499) Summary
Immunogen |
Synthetic peptide corresponding to C-terminus of human dystrophin.
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Specificity |
This product is specific for Dystrophin
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Isotype |
IgG1 Kappa
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Clonality |
Monoclonal
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Host |
Mouse
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Gene |
DMD
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Purity |
Protein A or G purified
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Applications/Dilutions
Dilutions |
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Application Notes |
IHC-P: Use at an assay dependent dilution. Staining of formalin fixed tissues requires boiling tissue sections in 10mMcitrate buffer, pH 6.0 for 10 min followed by cooling at room temperature for 20 min.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user.
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Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze.
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Buffer |
10mM PBS (pH 7.4) and 1.0% BSA
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Preservative |
0.1% Sodium Azide
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Purity |
Protein A or G purified
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Alternate Names for Dystrophin Antibody (SPM499)
- BMDDXS272
- CMD3B
- DXS142
- DXS164
- DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272
- DXS206
- DXS230
- DXS239
- DXS268
- DXS269
- DXS270
- dystrophin (muscular dystrophy, Duchenne and Becker types), includes DXS142
- dystrophin
Background
Dystrophin is a member of the spectrin/alpha-actinin family of actin-binding, triple helix rod-containing proteins. It is absent or greatly reduced in individuals with the X-linked recessive Duchennes muscular dystrophy disorder, as well as in mice with the mdx (murine muscular dystrophy) mutation.