Product: Lofexidine (hydrochloride)
DIDO1 Antibody Summary
Immunogen |
Synthetic peptide near the N-terminus of mouse Dio-1.
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Clonality |
Polyclonal
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Host |
Rabbit
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Gene |
DIDO1
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Purity |
Protein A purified
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Applications/Dilutions
Dilutions |
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Application Notes |
Western blotting (0.5-4 ug/ml). However, the optimal concentrations should be determined individually. Other applications have not been tested. The antibody recognizes the 62 kDa human and mouse Dio-1 in Western blot analysis. Jurkat cell lysate and mouse small intestine tissue lysate can be used as positive controls.
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Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles.
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Buffer |
PBS, 0.5% BSA and 30% Glycerol
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Preservative |
0.01% Thimerosal
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Purity |
Protein A purified
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Alternate Names for DIDO1 Antibody
- BYE1
- C20orf158
- DATF1
- DATF-1
- DATF1DIDO3
- death associated transcription factor 1
- death inducer-obliterator 1
- Death-associated transcription factor 1
- death-inducer obliterator 1
- DIDO1
- DIO1
- DIO1DIDO2
- DIO-1hDido1
- dJ885L7.8
- DKFZp434P1115
- FLJ11265
- KIAA0333chromosome 20 open reading frame 158
- MGC16140
Background
Apoptosis, a major form of cell death, is an efficient mechanism for eliminating unwanted cells and is of central importance for development and homeostasis in metazoan animals. In mice, the death inducer-obliterator-1 gene is upregulated by apoptotic signals and encodes a cytoplasmic protein that translocates to the nucleus upon apoptotic signal activation. When overexpressed, the mouse protein induced apoptosis in cell lines growing in vitro. This gene is similar to the mouse gene and therefore is thought to be involved in apoptosis. Alternatively spliced transcripts have been found for this gene, encoding multiple isoforms.