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Product: Chlorazanil (hydrochloride)

Nectin-3/PVRL3 Antibody Summary

Immunogen
Synthetic peptide corresponding to residues surrounding amino acids 536 of mouse Nectin-3.
Clonality
Polyclonal
Host
Rabbit
Gene
PVRL3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~ 83 kDa Nectin-3 of mouse and rat origins. Reactivity to other species has not been tested.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2), 0.5% BSA and 30% Glycerol
Preservative
0.01% Thimerosal
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Nectin-3/PVRL3 Antibody

  • CD113 antigen
  • CD113
  • CDw113FLJ90624
  • DKFZp566B0846
  • nectin 3
  • Nectin3
  • Nectin-3
  • poliovirus receptor-related 3
  • poliovirus receptor-related protein 3
  • PPR3
  • PRR3CD113
  • PVRL3
  • PVRR3

Background

Nectins (e.g., PVRL1; MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6; MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin (see MIM 192090)-catenin (see MIM 116805) system in epithelial cells.[supplied by OMIM]

PMID: 10723137

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Author: premierroofingandsidinginc