HCN3 Antibody Summary
Immunogen |
Peptide with sequence C-RGVRGRAPSTGAQ corresponding to internal region according to NP_065948.1.
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Epitope |
C-RGVRGRAPSTGAQ
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Clonality |
Polyclonal
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Host |
Goat
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Gene |
HCN3
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Purity |
Immunogen affinity purified
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Applications/Dilutions
Dilutions |
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Application Notes |
WB: Approx. 85 kDa band observed in rat kidney lysates (calculated MW of 86.0 kDa band according to human NP_065948.1 and 86.8 kDa band according to rat NP_446137.1).
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Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Human, Mouse, Canine, Bovine.
Packaging, Storage & Formulations
Storage |
Store at -20C. Avoid freeze-thaw cycles.
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Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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Preservative |
0.02% Sodium Azide
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Purity |
Immunogen affinity purified
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Alternate Names for HCN3 Antibody
- hyperpolarization activated cyclic nucleotide-gated potassium channel 3
- KIAA1535MGC131493
- potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3
Background
HCN3 is a member of the family of hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. HCN3 has been detected in the brain, but with less expression than other HCN channels.