Polycystin 2 Antibody Summary
| Immunogen |
Peptide with sequence C-ERAKLKRREVLGR corresponding to internal region according to NP_000288.1.
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| Epitope |
C-ERAKLKRREVLGR
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| Clonality |
Polyclonal
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| Host |
Goat
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| Gene |
PKD2
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| Purity |
Immunogen affinity purified
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Applications/Dilutions
| Dilutions |
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| Application Notes |
WB: Approx. 100 kDa band observed in HeLa lysate (calculated MW of 110 kDa band according to NP_000288.1).
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| Publications |
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Reactivity Notes
Predicted cross-reactivity based on sequence identity: Mouse, Rat, Bovine.
Packaging, Storage & Formulations
| Storage |
Store at -20C. Avoid freeze-thaw cycles.
|
| Buffer |
0.5 mg/ml Tris (pH 7.3) and 0.5% BSA
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| Preservative |
0.02% Sodium Azide
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| Concentration |
0.5 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for Polycystin 2 Antibody
- APKD2
- Autosomal dominant polycystic kidney disease type II protein
- MGC138466
- MGC138468
- PC2
- Pc-2
- PKD4
- polycystic kidney disease 2 (autosomal dominant)
- Polycystic kidney disease 2 protein
- polycystin-2
- polycystwin
- R48321
- transient receptor potential cation channel, subfamily P, member 2
- TRPP2
Background
FUNCTION: Functions as a calcium permeable cation channel. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. SUBUNIT: Interacts with PKD1. PKD1 requires the presence of PKD2 for stable expression. Interacts with CD2AP. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in mesenchymally derived structures in the developing embryo at day 12.5. In adult, mostly expressed in kidney.
