Product: Bicyclomycin benzoate
CACHD1 Antibody Summary
| Immunogen |
A synthetic peptide from the c-terminal region of CACHD1 conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is identical in mouse.
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| Specificity |
Appears to be specific for CACHD1.
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
CACHD1
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| Purity |
IgG purified
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Other species not yet tested.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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| Buffer |
No buffer
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| Preservative |
No Preservative
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| Concentration |
LYOPH
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| Purity |
IgG purified
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| Reconstitution Instructions |
Reconstitute with 0.5 ml sterilized water.
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Alternate Names for CACHD1 Antibody
- cache domain containing 1
- Cache domain-containing protein 1
- KIAA1573VWFA and cache domain-containing protein 1
- RP4-655E10.1
- von Willebrand factor type A and cache domain containing 1
- VWCD1
Background
FUNCTION: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Defects in CACNA2D4 are the cause of retinal cone dystrophy 4 (RCD4). RCD4 is characterized by minimal symptoms except for slowly progressive reduction in visual acuity.; Tissue specificity: Predominantly expressed in certain types of endocrine cells. Present in the Paneth cells of the small intestine. Also present in the erythroblasts in the fetal liver, in the cells of the zona reticularis of the adrenal gland and in the basophiles of the pituitary. Present at low level in some brain regions such as the cerebellum (at protein level).; Subcellular location: Membrane; Single-pass type I membrane protein; Miscellaneous: In contrast to CACNA2D1 and CACNA2D2, it does not bind gabapentin, an antiepileptic drug.
