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Product: S1p receptor agonist 1

CD-M6PR Antibody Summary

Immunogen
A synthetic peptide from the internal region of mouse MPRD (Cation dependent mannose-6-phosphate receptor) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat.
Specificity
MPRD.
Clonality
Polyclonal
Host
Rabbit
Gene
M6PR
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • Western Blot 10-50 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Mouse, rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Concentration
LYOPH
Purity
IgG purified
Reconstitution Instructions
Reconstitute with 0.5 ml sterilized water. Add glycerol (1:1) for additional stability.

Alternate Names for CD-M6PR Antibody

  • 000 Man6PR
  • 46 kDa mannose 6-phosphate receptor
  • 46-kDa mannose 6-phosphate receptor
  • cation-dependent mannose-6-phosphate receptor
  • CD Man-6-P receptor
  • CDM6PR
  • CD-M6PR
  • CD-MPR
  • FLJ32994
  • M6PR
  • mannose-6-phosphate receptor (cation dependent)
  • MPR 46
  • MPR46
  • MPRD
  • Mr 46
  • SMPR

Background

FUNCTION: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.; SUBUNIT: Homodimer. Binds GGA1, GGA2 and GGA3.; SUBCELLULAR LOCATION: Lysosome membrane; Single-pass type I membrane protein.

PMID: 16631081

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Author: premierroofingandsidinginc