Product: SKF89976A (hydrochloride)
Kv4.3 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the C-terminus region of human Kv4.3. The exact sequence is proprietary.
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| Localization |
Membrane; Multi-pass membrane protein; Cell membrane; sarcolemma
|
| Predicted Species |
Mouse (98%), Rat (99%), Rhesus Macaque (100%), Rabbit (97%), Bovine (100%). Backed by our 100% Guarantee.
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| Isotype |
IgG
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| Clonality |
Polyclonal
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| Host |
Rabbit
|
| Gene |
KCND3
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
73 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Chicken (84%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0), 1.0% BSA and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.88 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Kv4.3 Antibody
- KCND3L
- KCND3S
- KSHIVB
- Kv4.3
- MGC142035
- MGC142037
- potassium ionic channel Kv4.3
- potassium voltage-gated channel subfamily D member 3
- potassium voltage-gated channel, Shal-related subfamily, member 3
- sha1-related potassium channel Kv4.3
- voltage-gated K+ channel
- voltage-gated potassium channel Kv4.3
- Voltage-gated potassium channel subunit Kv4.3
Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes – shaker, shaw, shab, and shal – have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene. [provided by RefSeq]
