MST2/STK3 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human STK3. The exact sequence is proprietary.
|
| Localization |
Cytoplasm (By similarity); Nucleus (By similarity)
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
STK3
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovators Reward
|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
56 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.0) and 20% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
1 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for MST2/STK3 Antibody
- EC 2.7.11
- FLJ90748
- KRS1
- Mammalian STE20-like protein kinase 2
- Mess1
- MST2
- MST-2
- MST2EC 2.7.11.1
- MST3
- serine/threonine kinase 3 (STE20 homolog, yeast)
- serine/threonine kinase 3 (Ste20, yeast homolog)
- serine/threonine kinase 3
- serine/threonine-protein kinase 3
- Serine/threonine-protein kinase Krs-1
- STE20-like kinase MST2
- STK3
Background
Protein kinase activation is a frequent response of cells to treatment with growth factors, chemicals, heat shock, or apoptosis-inducing agents. This protein kinase activation presumably allows cells to resist unfavorable environmental conditions. The yeast sterile 20 (Ste20) kinase acts upstream of the mitogen-activated protein kinase (MAPK) cascade that is activated under a variety of stress conditions. MST2 was identified as a kinase that is activated by the proapoptotic agents straurosporine and FAS ligand (MIM 134638) (Taylor et al., 1996 [PubMed 8816758]; Lee et al., 2001 [PubMed 11278283]).[supplied by OMIM]
