Product: 5,15-Diacetyl-3-benzoyllathyrol
CD68/SR-D1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human CD68. The exact sequence is proprietary.
|
| Localization |
Isoform Short: Cell membrane; Isoform Long: Endosome membrane; Lysosome membrane
|
| Marker |
Histiocytic Marker
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
CD68
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.62 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for CD68/SR-D1 Antibody
- CD68 antigenmacrophage antigen CD68
- CD68 molecule
- CD68
- DKFZp686M18236
- gp110
- Macrosialin
- SCARD1
- scavenger receptor class D, member 1
- SRD1
- SR-D1
Background
This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq]
