NOB1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human NOB1. The exact sequence is proprietary.
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| Predicted Species |
Monkey (97%), Bovine (90%). Backed by our 100% Guarantee.
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| Isotype |
IgG
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
NOB1
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| Purity |
Immunogen affinity purified
|
| Innovators Reward |
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Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
47 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Rhesus Monkey (97%), Mouse (88%), Rat (88%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
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| Preservative |
0.01% Thimerosal
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| Concentration |
1.01 mg/ml
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| Purity |
Immunogen affinity purified
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Alternate Names for NOB1 Antibody
- adenocarcinoma antigen recognized by T lymphocytes 4
- ART4
- ART-4
- MST158
- nin one binding protein
- NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
- NOB1PPSMD8BP1
- Phosphorylation regulatory protein HP-10
- Protein ART-4
- PSMD8 binding protein 1
- RNA-binding protein NOB1
Background
In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]).[supplied by OMIM]
