Lambda5/IGLL1 Antibody Summary
| Immunogen |
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human IGLL1. The exact sequence is proprietary.
|
| Localization |
Secreted
|
| Isotype |
IgG
|
| Clonality |
Polyclonal
|
| Host |
Rabbit
|
| Gene |
IGLL1
|
| Purity |
Immunogen affinity purified
|
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
23 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 10% Glycerol
|
| Preservative |
0.01% Thimerosal
|
| Concentration |
0.4 mg/ml
|
| Purity |
Immunogen affinity purified
|
Alternate Names for Lambda5/IGLL1 Antibody
- 14.1
- AGM2
- CD179 antigen-like family member B
- CD179b antigen
- CD179b
- Ig lambda-5
- IGL1
- IGL5
- IGL5CD179B
- IGLJ14.1
- IGLL
- IGLL1
- IGO
- IGVPB
- immunoglobulin lambda-like polypeptide 1
- immunoglobulin omega polypeptide chain
- Immunoglobulin omega polypeptide
- immunoglobulin-related 14.1 protein
- Immunoglobulin-related protein 14.1
- Lambda5
- Pre-B lymphocyte-specific protein-2
- VPREB2
Background
The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
