Product: Histone Acetyltransferase Inhibitor II
MLH1 Antibody Summary
| Immunogen |
Recombinant protein encompassing a sequence within the center region of human MLH1. The exact sequence is proprietary.
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| Localization |
Nucleus
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| Predicted Species |
Mouse (95%), Rat (94%), Porcine (95%), Bovine (95%). Backed by our 100% Guarantee.
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| Isotype |
IgG
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| Clonality |
Polyclonal
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| Host |
Rabbit
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| Gene |
MLH1
|
| Purity |
Immunogen affinity purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
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| Application Notes |
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
|
| Theoretical MW |
85 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Reactivity Notes
Xenopus laevis (84%), Zebrafish (80%).
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
0.1M Tris (pH 7.0), 0.1M Glycine and 20% Glycerol
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| Preservative |
0.01% Thimerosal
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| Concentration |
0.83 mg/ml
|
| Purity |
Immunogen affinity purified
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Alternate Names for MLH1 Antibody
- COCA2FCC2
- DNA mismatch repair protein Mlh1
- hMLH1
- HNPCC
- HNPCC2MGC5172
- mutL (E. coli) homolog 1 (colon cancer, nonpolyposis type 2)
- mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
- MutL protein homolog 1
Background
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined. [provided by RefSeq]
