SETDB1 Antibody (5H6D4) Summary
| Immunogen |
Purified recombinant fragment of human SETDB1 expressed in E. Coli.
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| Isotype |
IgG1
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| Clonality |
Monoclonal
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| Host |
Mouse
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| Gene |
SETDB1
|
| Purity |
Unpurified
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| Innovators Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions
| Dilutions |
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Reactivity Notes
Human, Mouse, Primate. Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
Ascites
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| Preservative |
0.03% Sodium Azide
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| Purity |
Unpurified
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Alternate Names for SETDB1 Antibody (5H6D4)
- ERG-associated protein with SET domain
- ESETEC 2.1.1.43
- H3-K9-HMTase 4
- Histone H3-K9 methyltransferase 4
- histone-lysine N-methyltransferase SETDB1
- histone-lysine N-methyltransferase, H3lysine-9 specific 4
- KG1T
- KIAA0067H3-K9-HMTase4
- KMT1EERG-associated protein with a SET domain, ESET
- Lysine N-methyltransferase 1E
- SET domain bifurcated 1
- SET domain, bifurcated 1
Background
The SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su(var)3-9 and Enhancer of zeste proteins, from which the acronym SET is derived. Studies have suggested that the SET domain may be a signature of proteins that modulate transcriptionally active or repressed chromatin states through chromatin remodeling activities.[supplied by OMIM]
