Pax6 Antibody (1C8) Summary
| Immunogen |
Purified recombinant fragment of human PAX6 expressed in E. Coli.
|
| Marker |
Neural Marker
|
| Isotype |
IgG1
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
PAX6
|
| Purity |
Unpurified
|
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|
Applications/Dilutions
| Dilutions |
|
Reactivity Notes
Human
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
|
| Buffer |
Ascites
|
| Preservative |
0.03% Sodium Azide
|
| Purity |
Unpurified
|
Alternate Names for Pax6 Antibody (1C8)
- keratitis)
- MGC17209
- Oculorhombin
- paired box 6
- paired box protein Pax-6
- Pax6
Background
This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peters anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene.
